Cargando…

Anti-VEGF Signalling Mechanism in HUVECs by Melatonin, Serotonin, Hydroxytyrosol and Other Bioactive Compounds

Angiogenesis drives evolution and destabilisation of atherosclerotic plaques and the growth and expansion of tumour cells. Vascular endothelial growth factor (VEGF) is the main endogenous pro-angiogenic factor in humans. The aim was to provide insight into the anti-VEGF activity of bioactive compoun...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cerezo, Ana B., Labrador, María, Gutiérrez, Andrés, Hornedo-Ortega, Ruth, Troncoso, Ana M., Garcia-Parrilla, M. Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836248/ https://www.ncbi.nlm.nih.gov/pubmed/31614459 http://dx.doi.org/10.3390/nu11102421

Ejemplares similares

Inhibition of VEGF-Induced VEGFR-2 Activation and HUVEC Migration by Melatonin and Other Bioactive Indolic Compounds
por: Cerezo, Ana B., et al.
Publicado: (2017)

Anti-VEGF Effect of Bioactive Indolic Compounds and Hydroxytyrosol Metabolites
por: Gallardo-Fernández, Marta, et al.
Publicado: (2022)

Melatonin and Other Tryptophan Metabolites Produced by Yeasts: Implications in Cardiovascular and Neurodegenerative Diseases
por: Hornedo-Ortega, Ruth, et al.
Publicado: (2016)

Hydroxytyrosol Decreases LPS- and α-Synuclein-Induced Microglial Activation In Vitro
por: Gallardo-Fernández, Marta, et al.
Publicado: (2019)

Evidences of hydroxytyrosol as an anti-inflammatory agent in Parkinson’s disease: insights into the mechanisms of action
por: Hornedo-Ortega, Ruth, et al.
Publicado: (2020)

Hydroxytyrosol in Foods: Analysis, Food Sources, EU Dietary Intake, and Potential Uses
por: Gallardo-Fernández, Marta, et al.
Publicado: (2022)

Phenolic Compounds Characteristic of the Mediterranean Diet in Mitigating Microglia-Mediated Neuroinflammation
por: Hornedo-Ortega, Ruth, et al.
Publicado: (2018)

Bioactive Compounds Derived from the Yeast Metabolism of Aromatic Amino Acids during Alcoholic Fermentation
por: Mas, Albert, et al.
Publicado: (2014)

Anthocyanins in Blueberries Grown in Hot Climate Exert Strong Antioxidant Activity and May Be Effective against Urinary Tract Bacteria
por: Cerezo, Ana B., et al.
Publicado: (2020)

Sevoflurane promotes the proliferation of HUVECs by activating VEGF signaling
por: Wang, Zengtao, et al.
Publicado: (2020)

Winery By-Products as Sources of Bioactive Tryptophan, Serotonin, and Melatonin: Contributions to the Antioxidant Power
por: Baenas, Nieves, et al.
Publicado: (2023)

Hydroxytyrosol: The Phytochemical Responsible for Bioactivity of Traditionally used Olive Pits
por: Reis, Rengin, et al.
Publicado: (2018)

The Ionophoric Activity of a Pro-Apoptotic VEGF165 Fragment on HUVEC Cells
por: Zimbone, Stefania, et al.
Publicado: (2020)

Progress in Colloid Delivery Systems for Protection and Delivery of Phenolic Bioactive Compounds: Two Study Cases—Hydroxytyrosol and Curcumin
por: Cuomo, Francesca, et al.
Publicado: (2022)

Comparative Study of Hydroxytyrosol Acetate and Hydroxytyrosol in Activating Phase II Enzymes
por: Zou, Xuan, et al.
Publicado: (2023)

Melatonin Suppresses Hypoxia-Induced Migration of HUVECs via Inhibition of ERK/Rac1 Activation
por: Yang, Ling, et al.
Publicado: (2014)

Hydroxytyrosol, Tyrosol and Derivatives and Their Potential Effects on Human Health
por: Karković Marković, Ana, et al.
Publicado: (2019)

Serotonin and Melatonin in Human Lower Gastrointestinal Tract
por: Vaccaro, Rosa, et al.
Publicado: (2023)

Effects of hydroxytyrosol dose on the redox status of exercised rats: the role of hydroxytyrosol in exercise performance
por: Al Fazazi, Saad, et al.
Publicado: (2018)

ARPE-19-derived VEGF-containing exosomes promote neovascularization in HUVEC: the role of the melanocortin receptor 5
por: Maisto, Rosa, et al.
Publicado: (2019)

Evolution of Hydroxytyrosol, Hydroxytyrosol 4-β-d-Glucoside, 3,4-Dihydroxyphenylglycol and Tyrosol in Olive Oil Solid Waste or “Alperujo”
por: Fernández-Prior, África, et al.
Publicado: (2022)

A Three-Step, Gram-Scale Synthesis of Hydroxytyrosol, Hydroxytyrosol Acetate, and 3,4-Dihydroxyphenylglycol
por: Kalampaliki, Amalia D., et al.
Publicado: (2019)

VEGF Promotes the Transcription of the Human PRL-3 Gene in HUVEC through Transcription Factor MEF2C
por: Xu, Jianliang, et al.
Publicado: (2011)

Dietary Sources and Bioactivities of Melatonin
por: Meng, Xiao, et al.
Publicado: (2017)

The effects of melatonin on the concentrations of inflammatory cytokines and proteins, serotonin, cortisol and melatonin in ovariohysterectomised female dogs
por: Salavati, Sina, et al.
Publicado: (2023)

Absence of bioactivity of lipid derivatives of serotonin
por: Pozdzik, M, et al.
Publicado: (2010)

Impact of UVA exposure on psychological parameters and circulating serotonin and melatonin
por: Gambichler, Thilo, et al.
Publicado: (2002)

Microscopic Interactions of Melatonin, Serotonin and Tryptophan with Zwitterionic Phospholipid Membranes
por: Martí, Jordi, et al.
Publicado: (2021)

Oncostatic-Cytoprotective Effect of Melatonin and Other Bioactive Molecules: A Common Target in Mitochondrial Respiration
por: Pacini, Nicola, et al.
Publicado: (2016)

Redesigning of 3-Dimensional Vascular-Muscle Structure Using ADSCs/HUVECs Co-Culture and VEGF on Engineered Skeletal Muscle ECM
por: Heidari Moghadam, Abbas, et al.
Publicado: (2022)

Metabolic engineering of Saccharomyces cerevisiae for hydroxytyrosol overproduction directly from glucose
por: Bisquert, Ricardo, et al.
Publicado: (2021)

Synthesis and Antioxidant Activity of Alkyl Nitroderivatives of Hydroxytyrosol
por: Gallardo, Elena, et al.
Publicado: (2016)

Antidiabetic Effects of Hydroxytyrosol: In Vitro and In Vivo Evidence
por: Vlavcheski, Filip, et al.
Publicado: (2019)

Hydroxytyrosol and Cytoprotection: A Projection for Clinical Interventions
por: Echeverría, Francisca, et al.
Publicado: (2017)

Hydroxytyrosol in the Prevention of the Metabolic Syndrome and Related Disorders
por: Peyrol, Julien, et al.
Publicado: (2017)

Hydroxytyrosol as a Promising Ally in the Treatment of Fibromyalgia
por: Ramírez-Tejero, Jorge A., et al.
Publicado: (2020)

Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans
por: Boronat, Anna, et al.
Publicado: (2019)

Occurrence of Hydroxytyrosol, Tyrosol and Their Metabolites in Italian Cheese
por: Giusepponi, Danilo, et al.
Publicado: (2023)

Hydroxytyrosol: Its role in the prevention of cardiovascular diseases
por: Noguera-Navarro, Clara, et al.
Publicado: (2023)

An Aromatic Aldehyde Synthase Controls the Synthesis of Hydroxytyrosol Derivatives Present in Virgin Olive Oil
por: Sánchez, Rosario, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_15so40i8amf0805bgsqu6tq640