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Saccharomyces boulardii alleviates ulcerative colitis carcinogenesis in mice by reducing TNF-α and IL-6 levels and functions and by rebalancing intestinal microbiota

BACKGROUND AND AIMS: To explore the inhibition mechanism of Saccharomyces boulardii (S. boulardii) on ulcerative colitis (UC) carcinogenesis. METHODS: C57BL/6 mice were treated with azoxymethane and dextran sulfate sodium (AOM/DSS) to develop a UC carcinogenesis model. The treatment group was lavage...

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Detalles Bibliográficos
Autores principales: Wang, Chunsaier, Li, Wenbin, Wang, Hongying, Ma, Yiming, Zhao, Xinhua, Zhang, Xudong, Yang, Hong, Qian, Jiaming, Li, Jingnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836350/
https://www.ncbi.nlm.nih.gov/pubmed/31694526
http://dx.doi.org/10.1186/s12866-019-1610-8