Genomic interrogation of familial short stature contributes to the discovery of the pathophysiological mechanisms and pharmaceutical drug repositioning

BACKGROUND: Genetic factors, dysregulation in the endocrine system, cytokine and paracrine factors are implicated in the pathogenesis of familial short stature (FSS). Nowadays, the treatment choice for FSS is limited, with only recombinant human growth hormone (rhGH) being available. METHODS: Herein...

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Detalles Bibliográficos
Autores principales: Wong, Henry Sung-Ching, Lin, Ying-Ju, Lu, Hsing-Fang, Liao, Wen-Ling, Chen, Chien-Hsiun, Wu, Jer-Yuarn, Chang, Wei-Chiao, Tsai, Fuu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836357/
https://www.ncbi.nlm.nih.gov/pubmed/31699087
http://dx.doi.org/10.1186/s12929-019-0581-2

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