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NOTCH2 negatively regulates metastasis and epithelial-Mesenchymal transition via TRAF6/AKT in nasopharyngeal carcinoma

BACKGROUND: Clinically, distant metastasis after primary treatment remains a key problem in nasopharyngeal carcinoma (NPC). Thus, identification of the underlying mechanisms and development of novel therapeutic strategies are urgently needed. NOTCH has been shown to function as a tumor promotor that...

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Detalles Bibliográficos
Autores principales: Zou, You, Yang, Rui, Huang, Mao-Ling, Kong, Yong-Gang, Sheng, Jian-Fei, Tao, Ze-Zhang, Gao, Ling, Chen, Shi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836530/
https://www.ncbi.nlm.nih.gov/pubmed/31699119
http://dx.doi.org/10.1186/s13046-019-1463-x

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