DESE: estimating driver tissues by selective expression of genes associated with complex diseases or traits

The driver tissues or cell types in which susceptibility genes initiate diseases remain elusive. We develop a unified framework to detect the causal tissues of complex diseases or traits according to selective expression of disease-associated genes in genome-wide association studies (GWASs). This fr...

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Detalles Bibliográficos
Autores principales: Jiang, Lin, Xue, Chao, Dai, Sheng, Chen, Shangzhen, Chen, Peikai, Sham, Pak Chung, Wang, Haijun, Li, Miaoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836538/
https://www.ncbi.nlm.nih.gov/pubmed/31694669
http://dx.doi.org/10.1186/s13059-019-1801-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836538/
https://www.ncbi.nlm.nih.gov/pubmed/31694669
http://dx.doi.org/10.1186/s13059-019-1801-5

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