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Screening and computational analysis of colorectal associated non-synonymous polymorphism in CTNNB1 gene in Pakistani population

BACKGROUND: Colorectal cancer (CRC) is categorized by alteration of vital pathways such as β-catenin (CTNNB1) mutations, WNT signaling activation, tumor protein 53 (TP53) inactivation, BRAF, Adenomatous polyposis coli (APC) inactivation, KRAS, dysregulation of epithelial to mesenchymal transition (E...

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Detalles Bibliográficos
Autores principales:	Razak, Suhail, Bibi, Nousheen, Dar, Javid Ahmad, Afsar, Tayyaba, Almajwal, Ali, Parveen, Zahida, Jahan, Sarwat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836551/ https://www.ncbi.nlm.nih.gov/pubmed/31699039 http://dx.doi.org/10.1186/s12881-019-0911-y

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