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Blockade of IL-27 signaling ameliorates herpes stromal keratitis with upregulated CD4(+) Foxp3(+) regulatory T cells influx in mice

PURPOSE: The purpose of this study was to investigate the production of IL-27 p28 and EBI3 in the ocular inflammatory sites, and the role of IL-27 signaling in a model of HSV-1 induced herpetic stromal keratitis (HSK). METHODS: The BALB/c mice were injected intraperitoneally (24 h before infection)...

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Detalles Bibliográficos
Autores principales:	Xia, Likun, Tan, Tianchang, Li, Yang, Zhong, Qiuyue, Shi, Mei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer - Medknow 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836587/ https://www.ncbi.nlm.nih.gov/pubmed/31638041 http://dx.doi.org/10.4103/ijo.IJO_1780_18

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