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Apatinib potentiates irradiation effect via suppressing PI3K/AKT signaling pathway in hepatocellular carcinoma

BACKGROUND: Limited effective intervention for advanced hepatocellular carcinoma (HCC) is available. This study aimed to investigate the potential clinical utility of apatinib, a highly selective inhibitor of the vascular endothelial growth factor receptor-2 (VEGFR2) tyrosine kinase, as a radiosensi...

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Detalles Bibliográficos
Autores principales:	Liao, Junbin, Jin, Huilin, Li, Shaoqiang, Xu, Lixia, Peng, Zhenwei, Wei, Guangyan, Long, Jianting, Guo, Yu, Kuang, Ming, Zhou, Qi, Peng, Sui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836669/ https://www.ncbi.nlm.nih.gov/pubmed/31694662 http://dx.doi.org/10.1186/s13046-019-1419-1

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