Cargando…
Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention
Efficient clearance of transformed cells by Natural Killer (NK) cells is regulated by several activating receptors, including NKG2D, NCRs, and DNAM-1. Expression of these receptors as well as their specific “induced self” ligands is finely regulated during malignant transformation through the integr...
Autores principales: | Molfetta, Rosa, Zingoni, Alessandra, Santoni, Angela, Paolini, Rossella |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836727/ https://www.ncbi.nlm.nih.gov/pubmed/31736972 http://dx.doi.org/10.3389/fimmu.2019.02557 |
Ejemplares similares
-
NKG2D and Its Ligands: “One for All, All for One”
por: Zingoni, Alessandra, et al.
Publicado: (2018) -
NKG2D and DNAM-1 activating receptors and their ligands in NK-T cell interactions: role in the NK cell-mediated negative regulation of T cell responses
por: Zingoni, Alessandra, et al.
Publicado: (2013) -
Cereblon regulates NK cell cytotoxicity and migration via Rac1 activation
por: Fionda, Cinzia, et al.
Publicado: (2021) -
Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis
por: Molfetta, Rosa, et al.
Publicado: (2017) -
Regulation of Fc Receptor Endocytic Trafficking by Ubiquitination
por: Molfetta, Rosa, et al.
Publicado: (2014)