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Quantitative mitochondrial DNA copy number determination using droplet digital PCR with single-cell resolution

Mitochondria are involved in a number of diverse cellular functions, including energy production, metabolic regulation, apoptosis, calcium homeostasis, cell proliferation, and motility, as well as free radical generation. Mitochondrial DNA (mtDNA) is present at hundreds to thousands of copies per ce...

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Detalles Bibliográficos
Autores principales:	O'Hara, Ryan, Tedone, Enzo, Ludlow, Andrew, Huang, Ejun, Arosio, Beatrice, Mari, Daniela, Shay, Jerry W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2019
Materias:	Method
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836731/ https://www.ncbi.nlm.nih.gov/pubmed/31548359 http://dx.doi.org/10.1101/gr.250480.119

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