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ECG changes after percutaneous edge‐to‐edge mitral valve repair

BACKGROUND: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effecti...

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Autores principales: Bo, Hou, Heinzmann, David, Grasshoff, Christian, Rosenberger, Peter, Schlensak, Christian, Gawaz, Meinrad, Schreieck, Jürgen, Langer, Harald F., Patzelt, Johannes, Seizer, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837028/
https://www.ncbi.nlm.nih.gov/pubmed/31497886
http://dx.doi.org/10.1002/clc.23258
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author Bo, Hou
Heinzmann, David
Grasshoff, Christian
Rosenberger, Peter
Schlensak, Christian
Gawaz, Meinrad
Schreieck, Jürgen
Langer, Harald F.
Patzelt, Johannes
Seizer, Peter
author_facet Bo, Hou
Heinzmann, David
Grasshoff, Christian
Rosenberger, Peter
Schlensak, Christian
Gawaz, Meinrad
Schreieck, Jürgen
Langer, Harald F.
Patzelt, Johannes
Seizer, Peter
author_sort Bo, Hou
collection PubMed
description BACKGROUND: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high‐risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. HYPOTHESIS: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. METHODS: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow‐up. RESULTS: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P < .05, respectively). CONCLUSION: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm.
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spelling pubmed-68370282019-11-12 ECG changes after percutaneous edge‐to‐edge mitral valve repair Bo, Hou Heinzmann, David Grasshoff, Christian Rosenberger, Peter Schlensak, Christian Gawaz, Meinrad Schreieck, Jürgen Langer, Harald F. Patzelt, Johannes Seizer, Peter Clin Cardiol Clinical Investigations BACKGROUND: Mitral regurgitation (MR) has a severe impact on hemodynamics and induces severe structural changes in the left atrium. Atrial remodeling is known to alter excitability and conduction in the atrium facilitating atrial fibrillation and atrial flutter. PMVR is a feasible and highly effective procedure to reduce MR in high‐risk patients, which are likely to suffer from atrial rhythm disturbances. So far, electroanatomical changes after PMVR have not been studied. HYPOTHESIS: In the current study, we investigated changes in surface electrocardiograms (ECGs) of patients undergoing PMVR for reduction of MR. METHODS: We evaluated 104 surface ECGs from patients in sinus rhythm undergoing PMVR. P wave duration, P wave amplitude, PR interval, QRS duration, QRS axis, and QT interval were evaluated before and after PMVR and at follow‐up. RESULTS: We found no changes in QRS duration, QRS axis, and QT interval after successful PMVR. However, P wave duration, amplitude, and PR interval were significantly decreased after reduction of MR through PMVR (P < .05, respectively). CONCLUSION: The data we provide offers insight into changes in atrial conduction after reduction of MR using PMVR in patients with sinus rhythm. Wiley Periodicals, Inc. 2019-09-09 /pmc/articles/PMC6837028/ /pubmed/31497886 http://dx.doi.org/10.1002/clc.23258 Text en © 2019 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Investigations
Bo, Hou
Heinzmann, David
Grasshoff, Christian
Rosenberger, Peter
Schlensak, Christian
Gawaz, Meinrad
Schreieck, Jürgen
Langer, Harald F.
Patzelt, Johannes
Seizer, Peter
ECG changes after percutaneous edge‐to‐edge mitral valve repair
title ECG changes after percutaneous edge‐to‐edge mitral valve repair
title_full ECG changes after percutaneous edge‐to‐edge mitral valve repair
title_fullStr ECG changes after percutaneous edge‐to‐edge mitral valve repair
title_full_unstemmed ECG changes after percutaneous edge‐to‐edge mitral valve repair
title_short ECG changes after percutaneous edge‐to‐edge mitral valve repair
title_sort ecg changes after percutaneous edge‐to‐edge mitral valve repair
topic Clinical Investigations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837028/
https://www.ncbi.nlm.nih.gov/pubmed/31497886
http://dx.doi.org/10.1002/clc.23258
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