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Poly-arginine-18 peptides do not exacerbate bleeding, or improve functional outcomes following collagenase-induced intracerebral hemorrhage in the rat

BACKGROUND: Cationic arginine-rich peptides (CARPs) have demonstrated neuroprotective and/or behavioural efficacy in ischemic and hemorrhagic stroke and traumatic brain injury models. Therefore, in this study we investigated the safety and neuroprotective efficacy of the CARPs poly-arginine-18 (R18;...

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Detalles Bibliográficos
Autores principales:	Liddle, Lane, Reinders, Ryan, South, Samantha, Blacker, David, Knuckey, Neville, Colbourne, Frederick, Meloni, Bruno
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837498/ https://www.ncbi.nlm.nih.gov/pubmed/31697775 http://dx.doi.org/10.1371/journal.pone.0224870

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