Cargando…
Evolution of the nonsense-mediated decay pathway is associated with decreased cytolytic immune infiltration
The somatic co-evolution of tumors and the cellular immune responses that combat them drives the diversity of immune-tumor interactions. This includes tumor mutations that generate neo-antigenic epitopes that elicit cytotoxic T-cell activity and subsequent pressure to select for genetic loss of anti...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837539/ https://www.ncbi.nlm.nih.gov/pubmed/31658270 http://dx.doi.org/10.1371/journal.pcbi.1007467 |