Bacterial biodiversity drives the evolution of CRISPR-based phage resistance

Approximately half of all bacterial species encode CRISPR-Cas adaptive immune systems(1), which provide immunological memory by inserting short DNA sequences from phage and other parasitic DNA elements into CRISPR loci on the host genome(2). Whereas CRISPR loci evolve rapidly in natural environments...

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Detalles Bibliográficos
Autores principales: Alseth, Ellinor O, Pursey, Elizabeth, Luján, Adela M, McLeod, Isobel, Rollie, Clare, Westra, Edze R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837874/
https://www.ncbi.nlm.nih.gov/pubmed/31645729
http://dx.doi.org/10.1038/s41586-019-1662-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6837874/
https://www.ncbi.nlm.nih.gov/pubmed/31645729
http://dx.doi.org/10.1038/s41586-019-1662-9

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