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Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence
Cushing’s disease (CD) is a rare endocrine condition caused by a corticotroph pituitary tumor that produces adrenocorticotropic hormone. The current state of knowledge of CD treatment is presented in this article including factors that can be helpful in predicting remission and/or recurrence of the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838046/ https://www.ncbi.nlm.nih.gov/pubmed/31701434 http://dx.doi.org/10.1007/s12020-019-02036-2 |
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author | Pasternak-Pietrzak, Katarzyna Moszczyńska, Elżbieta Szalecki, Mieczysław |
author_facet | Pasternak-Pietrzak, Katarzyna Moszczyńska, Elżbieta Szalecki, Mieczysław |
author_sort | Pasternak-Pietrzak, Katarzyna |
collection | PubMed |
description | Cushing’s disease (CD) is a rare endocrine condition caused by a corticotroph pituitary tumor that produces adrenocorticotropic hormone. The current state of knowledge of CD treatment is presented in this article including factors that can be helpful in predicting remission and/or recurrence of the disease. The primary goals in CD treatment are quick diagnosis and effective, prompt treatment as the persistent disease is associated with increased morbidity and mortality. Cooperation of a team consisting of experienced pediatrician/adult endocrinologist, neuroradiologist, transsphenoidal neurosurgeon and (if necessary) radiotherapist contribute to the best treatment effects. |
format | Online Article Text |
id | pubmed-6838046 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-68380462019-11-20 Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence Pasternak-Pietrzak, Katarzyna Moszczyńska, Elżbieta Szalecki, Mieczysław Endocrine Review Cushing’s disease (CD) is a rare endocrine condition caused by a corticotroph pituitary tumor that produces adrenocorticotropic hormone. The current state of knowledge of CD treatment is presented in this article including factors that can be helpful in predicting remission and/or recurrence of the disease. The primary goals in CD treatment are quick diagnosis and effective, prompt treatment as the persistent disease is associated with increased morbidity and mortality. Cooperation of a team consisting of experienced pediatrician/adult endocrinologist, neuroradiologist, transsphenoidal neurosurgeon and (if necessary) radiotherapist contribute to the best treatment effects. Springer US 2019-11-07 2019 /pmc/articles/PMC6838046/ /pubmed/31701434 http://dx.doi.org/10.1007/s12020-019-02036-2 Text en © The Author(s) 2019 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Review Pasternak-Pietrzak, Katarzyna Moszczyńska, Elżbieta Szalecki, Mieczysław Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence |
title | Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence |
title_full | Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence |
title_fullStr | Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence |
title_full_unstemmed | Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence |
title_short | Treatment challenges in pediatric Cushing’s disease: Review of the literature with particular emphasis on predictive factors for the disease recurrence |
title_sort | treatment challenges in pediatric cushing’s disease: review of the literature with particular emphasis on predictive factors for the disease recurrence |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838046/ https://www.ncbi.nlm.nih.gov/pubmed/31701434 http://dx.doi.org/10.1007/s12020-019-02036-2 |
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