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Acetylation of conserved DVL-1 lysines regulates its nuclear translocation and binding to gene promoters in triple-negative breast cancer
Dishevelled (DVL) proteins are central mediators of the Wnt signalling pathway and are versatile regulators of several cellular processes, yet little is known about their post-translational regulation. Acetylation is a reversible post-translational modification (PTM) which regulates the function of...
Autores principales: | Sharma, Monica, Molehin, Deborah, Castro-Piedras, Isabel, Martinez, Edgar G., Pruitt, Kevin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838061/ https://www.ncbi.nlm.nih.gov/pubmed/31700102 http://dx.doi.org/10.1038/s41598-019-52723-3 |
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