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PI3-Kinase δγ Catalytic Isoforms Regulate the Th-17 Response in Tuberculosis
Although IL17A plays a protective role at the mucosal surface, when IL17A signaling becomes dysregulated, a pathological response is locally induced. At the early stages of Mycobacterium tuberculosis (M.tb) infection, IL17A contributes to granuloma formation and pathogen containment. In contrast, du...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838131/ https://www.ncbi.nlm.nih.gov/pubmed/31736982 http://dx.doi.org/10.3389/fimmu.2019.02583 |