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New diphenylphosphane derivatives of ketoconazole are promising antifungal agents

Four new derivatives of ketoconazole (Ke) were synthesized: diphenylphosphane (KeP), and phosphane chalcogenides: oxide (KeOP), sulphide (KeSP) and selenide (KeSeP). These compounds proved to be promising antifungal compounds towards Saccharomyces cerevisiae and Candida albicans, especially in syner...

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Detalles Bibliográficos
Autores principales: de Almeida, Rodrigo F. M., Santos, Filipa C., Marycz, Krzysztof, Alicka, Michalina, Krasowska, Anna, Suchodolski, Jakub, Panek, Jarosław J., Jezierska, Aneta, Starosta, Radosław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838151/
https://www.ncbi.nlm.nih.gov/pubmed/31700024
http://dx.doi.org/10.1038/s41598-019-52525-7