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Defining the Celiac Disease Transcriptome using Clinical Pathology Specimens Reveals Biologic Pathways and Supports Diagnosis

Celiac disease is provoked by gluten exposure, but the complete pathogenic process in the duodenum and the loss of tolerance to gluten is not well understood. We aimed to define the core celiac transcriptomic signature and pathologic pathways in pre-treatment formalin-fixed paraffin-embedded (FFPE)...

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Detalles Bibliográficos
Autores principales: Loberman-Nachum, Nurit, Sosnovski, Katya, Di Segni, Ayelet, Efroni, Gilat, Braun, Tzipi, BenShoshan, Marina, Anafi, Lait, Avivi, Camila, Barshack, Iris, Shouval, Dror S., Denson, Lee A., Amir, Amnon, Unger, Ron, Weiss, Batia, Haberman, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838157/
https://www.ncbi.nlm.nih.gov/pubmed/31700112
http://dx.doi.org/10.1038/s41598-019-52733-1