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Defining the Celiac Disease Transcriptome using Clinical Pathology Specimens Reveals Biologic Pathways and Supports Diagnosis
Celiac disease is provoked by gluten exposure, but the complete pathogenic process in the duodenum and the loss of tolerance to gluten is not well understood. We aimed to define the core celiac transcriptomic signature and pathologic pathways in pre-treatment formalin-fixed paraffin-embedded (FFPE)...
Autores principales: | Loberman-Nachum, Nurit, Sosnovski, Katya, Di Segni, Ayelet, Efroni, Gilat, Braun, Tzipi, BenShoshan, Marina, Anafi, Lait, Avivi, Camila, Barshack, Iris, Shouval, Dror S., Denson, Lee A., Amir, Amnon, Unger, Ron, Weiss, Batia, Haberman, Yael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838157/ https://www.ncbi.nlm.nih.gov/pubmed/31700112 http://dx.doi.org/10.1038/s41598-019-52733-1 |
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