p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway

Centrosomal p53 has been described for three decades but its role is still unclear. We previously reported that, in proliferating human cells, p53 transiently moves to centrosomes at each mitosis. Such p53 mitotic centrosome localization (p53-MCL) occurs independently from DNA damage but requires AT...

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Detalles Bibliográficos
Autores principales: Contadini, Claudia, Monteonofrio, Laura, Virdia, Ilaria, Prodosmo, Andrea, Valente, Davide, Chessa, Luciana, Musio, Antonio, Fava, Luca L., Rinaldo, Cinzia, Di Rocco, Giuliana, Soddu, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838180/
https://www.ncbi.nlm.nih.gov/pubmed/31699974
http://dx.doi.org/10.1038/s41419-019-2076-1

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