Cargando…

The Cholesteryl Ester Transfer Protein Inhibitor, des-Fluoro-Anacetrapib, Prevents Vein Bypass-induced Neointimal Hyperplasia in New Zealand White Rabbits

Coronary artery bypass grafting is among the most commonly performed of all cardiovascular surgical procedures. However, graft failure due to stenosis reduces the long-term benefit of the intervention. This study asks if elevating plasma high density lipoprotein cholesterol (HDL-C) levels by inhibit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Ben J., Li, Yue., Ong, Kwok-Leung, Sun, Yidan, Johns, Douglas, Barter, Philip J., Rye, Kerry-Anne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838195/ https://www.ncbi.nlm.nih.gov/pubmed/31700015 http://dx.doi.org/10.1038/s41598-019-52510-0

Ejemplares similares

How Anacetrapib Inhibits the Activity of the Cholesteryl Ester Transfer Protein? Perspective through Atomistic Simulations
por: Äijänen, Tarja, et al.
Publicado: (2014)

Patient considerations and clinical impact of cholesteryl ester transfer protein inhibitors in the management of dyslipidemia: focus on anacetrapib
por: Miyares, Marta A, et al.
Publicado: (2012)

Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case
por: Johns, Douglas G., et al.
Publicado: (2019)

CETP (Cholesteryl Ester Transfer Protein) Inhibition With Anacetrapib Decreases Production of Lipoprotein(a) in Mildly Hypercholesterolemic Subjects
por: Thomas, Tiffany, et al.
Publicado: (2017)

Assessing the mechanisms of cholesteryl ester transfer protein inhibitors
por: Zhang, Meng, et al.
Publicado: (2017)

Dalcetrapib and anacetrapib differently impact HDL structure and function in rabbits and monkeys
por: Brodeur, Mathieu R., et al.
Publicado: (2017)

Dalcetrapib and anacetrapib increase apolipoprotein E-containing HDL in rabbits and humans
por: Brodeur, Mathieu R., et al.
Publicado: (2022)

Atorvastatin and Fenofibrate Increase the Content of Unsaturated Acyl Chains in HDL and Modify In Vivo Kinetics of HDL-Cholesteryl Esters in New Zealand White Rabbits
por: Flores-Castillo, Cristóbal, et al.
Publicado: (2019)

Anacetrapib as a potential cardioprotective strategy
por: Di Bartolo, Belinda A, et al.
Publicado: (2017)

Atorvastatin improves cisplatin sensitivity through modulation of cholesteryl ester homeostasis in breast cancer cells
por: Zipinotti dos Santos, Diandra, et al.
Publicado: (2022)

The effects of PPARγ agonist rosiglitazone on neointimal hyperplasia in rabbit carotid anastomosis model
por: Guzeloglu, Mehmet, et al.
Publicado: (2012)

In vivo endothelialization and neointimal hyperplasia assessment after rabbit carotid endarterectomy with bovine pericardium
por: Chen, Yanfei, et al.
Publicado: (2021)

Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors
por: Chapman, M. John, et al.
Publicado: (2010)

Impact of ADCY9 Genotype on Response to Anacetrapib
por: Hopewell, Jemma C., et al.
Publicado: (2019)

Prostate cancer cell proliferation is influenced by LDL-cholesterol availability and cholesteryl ester turnover
por: Raftopulos, Nikki L., et al.
Publicado: (2022)

Pretreatment with intraluminal rapamycin nanoparticle perfusion inhibits neointimal hyperplasia in a rabbit vein graft model
por: Liu, Kai, et al.
Publicado: (2010)

Concentration dependent cholesteryl-ester and wax-ester structural relationships and meibomian gland dysfunction
por: Hetman, Zofia A., et al.
Publicado: (2020)

Reversible accumulation of cholesteryl esters in macrophages incubated with acetylated lipoproteins
Publicado: (1979)

Cholesteryl ester transfer protein inhibitors for dyslipidemia: focus on dalcetrapib
por: Goldberg, Alyse S, et al.
Publicado: (2012)

Cholesteryl Ester Transfer Protein Gene Polymorphisms and Longevity Syndrome
por: Kolovou, Genovefa, et al.
Publicado: (2010)

Cholesteryl Ester Transfer Protein (CETP) Deficiency and CETP Inhibitors
por: Mabuchi, Hiroshi, et al.
Publicado: (2014)

Fluorescent Sterols and Cholesteryl Esters as Probes for Intracellular Cholesterol Transport
por: Solanko, Katarzyna A., et al.
Publicado: (2016)

Structure-based mechanism and inhibition of cholesteryl ester transfer protein
por: Xue, Han, et al.
Publicado: (2023)

Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits
por: Gao, Shoucui, et al.
Publicado: (2017)

Long-term safety and efficacy of anacetrapib in patients with atherosclerotic vascular disease
por: Sammons, E, et al.
Publicado: (2021)

A mathematical model of venous neointimal hyperplasia formation
por: Budu-Grajdeanu, Paula, et al.
Publicado: (2008)

Corrigendum to “Overexpression of Cholesteryl Ester Transfer Protein Increases Macrophage-Derived Foam Cell Accumulation in Atherosclerotic Lesions of Transgenic Rabbits”
por: Gao, Shoucui, et al.
Publicado: (2018)

Cholesteryl Ester Transfer Protein Gene and Effectiveness of Lipid Lowering of Atorvastatin
por: Kolovou, Genovefa, et al.
Publicado: (2010)

Cholesteryl Esters Accumulate in the Heart in a Porcine Model of Ischemia and Reperfusion
por: Drevinge, Christina, et al.
Publicado: (2013)

The Proteome of Cholesteryl-Ester-Enriched Versus Triacylglycerol-Enriched Lipid Droplets
por: Khor, Victor K., et al.
Publicado: (2014)

Cholesteryl ester transfer protein: ace of spades, queen of hearts, or the joker?
por: Miller, Norman E.
Publicado: (2015)

REVEAL Study: Reveals the Limitations of Cholesteryl Ester Transfer Protein Inhibition
por: Pareek, Anil, et al.
Publicado: (2018)

Cholesterol is Inefficiently Converted to Cholesteryl Esters in the Blood of Cardiovascular Disease Patients
por: Gerl, Mathias J., et al.
Publicado: (2018)

Cholesteryl ester levels are elevated in the caudate and putamen of Huntington’s disease patients
por: Phillips, Gabrielle R., et al.
Publicado: (2020)

Correlation of cholesteryl ester metabolism to pathogenesis, progression and disparities in colorectal Cancer
por: Liu, Zhirong, et al.
Publicado: (2022)

The cholesteryl ester transfer protein (CETP) raises cholesterol levels in the brain
por: Oestereich, Felix, et al.
Publicado: (2022)

miRNA‐200c‐3p promotes endothelial to mesenchymal transition and neointimal hyperplasia in artery bypass grafts
por: Chen, Dan, et al.
Publicado: (2020)

Fluid upstream shear stress of rabbit aortic stenosis inhibits neointimal hyperplasia by promoting endothelization after balloon injury
por: Liu, Jinxue, et al.
Publicado: (2017)

Hepatocyte-specific deletion of lysosomal acid lipase leads to cholesteryl ester but not triglyceride or retinyl ester accumulation
por: Pajed, Laura, et al.
Publicado: (2019)

Role of Hypoxia and Metabolism in the Development of Neointimal Hyperplasia in Arteriovenous Fistulas
por: Sadaghianloo, Nirvana, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_dus5hph3m2he8v1do8o61iu5r6