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Inhibition of STAT3 in tubular epithelial cells prevents kidney fibrosis and nephropathy in STZ-induced diabetic mice

Recent evidences indicate that signal transducer and activator of transcription 3 (STAT3) is one of the crucial signaling pathways in the progression of diabetic nephropathy (DN). Here, we investigated the hypothesis that pharmacological blockade of STAT3 limits the progression of DN. Treatment with...

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Detalles Bibliográficos
Autores principales:	Zheng, Chao, Huang, Lan, Luo, Wu, Yu, Weihui, Hu, Xueting, Guan, Xinfu, Cai, Yan, Zou, Chunpeng, Yin, Haimin, Xu, Zheng, Liang, Guang, Wang, Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838321/ https://www.ncbi.nlm.nih.gov/pubmed/31699972 http://dx.doi.org/10.1038/s41419-019-2085-0

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