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The inflammasome NLRP3 plays a dual role on mouse corpora cavernosa relaxation

NLRP3 plays a role in vascular diseases. Corpora cavernosa (CC) is an extension of the vasculature. We hypothesize that NLRP3 plays a deleterious role in CC relaxation. Male C57BL/6 (WT) and NLRP3 deficient (NLRP3(−/−)) mice were used. Intracavernosal pressure (ICP/MAP) measurement was performed. Fu...

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Detalles Bibliográficos
Autores principales: Fais, Rafael S., Rodrigues, Fernanda L., Pereira, Camila A., Mendes, Allan C., Mestriner, Fabíola, Tostes, Rita C., Carneiro, Fernando S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838322/
https://www.ncbi.nlm.nih.gov/pubmed/31700106
http://dx.doi.org/10.1038/s41598-019-52831-0