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Independent control of the thermodynamic and kinetic properties of aptamer switches

Molecular switches that change their conformation upon target binding offer powerful capabilities for biotechnology and synthetic biology. Aptamers are useful as molecular switches because they offer excellent binding properties, undergo reversible folding, and can be engineered into many nanostruct...

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Detalles Bibliográficos
Autores principales: Wilson, Brandon D., Hariri, Amani A., Thompson, Ian A. P., Eisenstein, Michael, Soh, H. Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838323/
https://www.ncbi.nlm.nih.gov/pubmed/31699984
http://dx.doi.org/10.1038/s41467-019-13137-x