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MicroRNA-495 downregulates AQP1 and facilitates proliferation and differentiation of osteoblasts in mice with tibial fracture through activation of p38 MAPK signaling pathway

Osteoblasts are implicated in the building of the vertebrate skeleton. The current study aimed to investigate the role of microRNA-495 (miR-495) in the osteoblasts of mice with tibial fractures and the underlying mechanism involving in aquaporin-1 (AQP1) and the p38 mitogen-activated protein kinase...

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Detalles Bibliográficos
Autores principales: Zhu, Lei, Lin, Zun-Wen, Wang, Gang, Zhang, Hong, Liu, Ben, Xu, Qing-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838328/
https://www.ncbi.nlm.nih.gov/pubmed/31700003
http://dx.doi.org/10.1038/s41598-019-50013-6