Cargando…
Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia
The oncogenic fusion protein AML1-ETO retains the ability of AML1 to interact with the enhancer core DNA sequences, but blocks AML1-dependent transcription. Previous studies have shown that post-translational modification of AML1-ETO may play a role in its regulation. Here we report that AML1-ETO-po...
Autores principales: | Dou, Liping, Yan, Fei, Pang, Jiuxia, Zheng, Dehua, Li, Dandan, Gao, Li, Wang, Lijun, Xu, Yihan, Shi, Jinlong, Wang, Qian, Zhou, Lei, Shen, Na, Singh, Puja, Wang, Lili, Li, Yonghui, Gao, Yvchi, Liu, Tao, Chen, Chongjian, Al-Kali, Aref, Litzow, Mark R., Chi, Young-In, Bode, Ann M., Liu, Chunhui, Huang, Haojie, Liu, Daihong, Marcucci, Guido, Liu, Shujun, Yu, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838331/ https://www.ncbi.nlm.nih.gov/pubmed/31699991 http://dx.doi.org/10.1038/s41467-019-12960-6 |
Ejemplares similares
-
A novel epigenetic AML1‐ETO/THAP10/miR‐383 mini‐circuitry contributes to t(8;21) leukaemogenesis
por: Li, Yonghui, et al.
Publicado: (2017) -
CALCRL Gene is a Suitable Prognostic Factor in AML/ETO(+) AML Patients
por: Wang, Rongrong, et al.
Publicado: (2022) -
A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis
por: Shen, Na, et al.
Publicado: (2014) -
A dynamic N(6)-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors
por: Yan, Fei, et al.
Publicado: (2018) -
AML1-ETO-Related Fusion Circular RNAs Contribute to the Proliferation of Leukemia Cells
por: Wang, Ying, et al.
Publicado: (2022)