Cinobufotalin powerfully reversed EBV-miR-BART22-induced cisplatin resistance via stimulating MAP2K4 to antagonize non-muscle myosin heavy chain IIA/glycogen synthase 3β/β-catenin signaling pathway

BACKGROUND: Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-related tumor. The role of EBV-encoding miR-BART22 is still unclear in NPC. This study aimed to identify the detailed mechanisms by which EBV-miR-BART22 functions as a tumor-promoting factor and evaluate the action of cinobufo...

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Detalles Bibliográficos
Autores principales: Liu, Yiyi, Jiang, Qingping, Liu, Xiong, Lin, Xian, Tang, ZiBo, Liu, Chen, Zhou, Jin, Zhao, Mengyang, Li, Xin, Cheng, Zhao, Li, Libo, Xie, Yingying, Liu, Zhen, Fang, Weiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838365/
https://www.ncbi.nlm.nih.gov/pubmed/31594754
http://dx.doi.org/10.1016/j.ebiom.2019.08.040

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