Generation of in situ sequencing based OncoMaps to spatially resolve gene expression profiles of diagnostic and prognostic markers in breast cancer

BACKGROUND: Gene expression analysis of breast cancer largely relies on homogenized tissue samples. Due to the high degree of cellular and molecular heterogeneity of tumor tissues, bulk tissue-based analytical approaches can only provide very limited system-level information about different signalin...

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Detalles Bibliográficos
Autores principales: Svedlund, Jessica, Strell, Carina, Qian, Xiaoyan, Zilkens, Kilian J.C., Tobin, Nicholas P., Bergh, Jonas, Sieuwerts, Anieta M., Nilsson, Mats
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838368/
https://www.ncbi.nlm.nih.gov/pubmed/31526717
http://dx.doi.org/10.1016/j.ebiom.2019.09.009

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