Knockdown of vimentin reduces mesenchymal phenotype of cholangiocytes in the Mdr2(−/−) mouse model of primary sclerosing cholangitis (PSC)

BACKGROUND: Cholangiocytes are the target cells of cholangiopathies including primary sclerosing cholangitis (PSC). Vimentin is an intermediate filament protein that has been found in various types of mesenchymal cells. The aim of this study is to evaluate the role of vimentin in the progression of...

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Detalles Bibliográficos
Autores principales: Zhou, Tianhao, Kyritsi, Konstantina, Wu, Nan, Francis, Heather, Yang, Zhihong, Chen, Lixian, O'Brien, April, Kennedy, Lindsey, Ceci, Ludovica, Meadows, Vik, Kusumanchi, Praveen, Wu, Chaodong, Baiocchi, Leonardo, Skill, Nicholas J., Saxena, Romil, Sybenga, Amelia, Xie, Linglin, Liangpunsakul, Suthat, Meng, Fanyin, Alpini, Gianfranco, Glaser, Shannon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838376/
https://www.ncbi.nlm.nih.gov/pubmed/31522982
http://dx.doi.org/10.1016/j.ebiom.2019.09.013

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