Redefining malignant pleural mesothelioma types as a continuum uncovers immune-vascular interactions

BACKGROUND: Malignant Pleural Mesothelioma (MPM) is an aggressive disease related to asbestos exposure, with no effective therapeutic options. METHODS: We undertook unsupervised analyses of RNA-sequencing data of 284 MPMs, with no assumption of discreteness. Using immunohistochemistry, we performed...

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Detalles Bibliográficos
Autores principales: Alcala, Nicolas, Mangiante, Lise, Le-Stang, Nolwenn, Gustafson, Corinne E., Boyault, Sandrine, Damiola, Francesca, Alcala, Karine, Brevet, Marie, Thivolet-Bejui, Françoise, Blanc-Fournier, Cécile, Le Rochais, Jean-Philippe, Planchard, Gaëtane, Rousseau, Nathalie, Damotte, Diane, Pairon, Jean Claude, Copin, Marie Christine, Scherpereel, Arnaud, Wasielewski, Eric, Wicquart, Laurence, Lacomme, Stéphanie, Vignaud, Jean-Michel, Ancelin, Gaspard, Girard, Cécile, Sagan, Christine, Bonnetaud, Christelle, Hofman, Véronique, Hofman, Paul, Mouroux, Jérôme, Thomas de Montpreville, Vincent, Clermont-Taranchon, Estelle, Mazieres, Julien, Rouquette, Isabelle, Begueret, Hugues, Blay, Jean-Yves, Lantuejoul, Sylvie, Bueno, Raphael, Caux, Christophe, Girard, Nicolas, McKay, James D., Foll, Matthieu, Galateau-Salle, Françoise, Fernandez-Cuesta, Lynnette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838392/
https://www.ncbi.nlm.nih.gov/pubmed/31648983
http://dx.doi.org/10.1016/j.ebiom.2019.09.003

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