Hepatic encephalopathy is linked to alterations of autophagic flux in astrocytes

BACKGROUND: Hepatic encephalopathy (HE) is a severe neuropsychiatric syndrome caused by various types of liver failure resulting in hyperammonemia-induced dysfunction of astrocytes. It is unclear whether autophagy, an important pro-survival pathway, is altered in the brains of ammonia-intoxicated an...

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Detalles Bibliográficos
Autores principales: Lu, Kaihui, Zimmermann, Marcel, Görg, Boris, Bidmon, Hans-Jürgen, Biermann, Barbara, Klöcker, Nikolaj, Häussinger, Dieter, Reichert, Andreas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838440/
https://www.ncbi.nlm.nih.gov/pubmed/31648987
http://dx.doi.org/10.1016/j.ebiom.2019.09.058

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