New insight into Alzheimer's disease: Light reverses Aβ-obstructed interstitial fluid flow and ameliorates memory decline in APP/PS1 mice

INTRODUCTION: Pharmacological therapies to treat Alzheimer's disease (AD) targeting “Aβ” have failed for over 100 years. Low levels of laser light can disassemble Aβ. In this study, we investigated the mechanisms that Aβ-blocked extracellular space (ECS) induces memory disorders in APP/PS1 tran...

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Detalles Bibliográficos
Autores principales: Yue, Xiangpei, Mei, Yufei, Zhang, Yun, Tong, Zheng, Cui, Dehua, Yang, Jun, Wang, Aibo, Wang, Rui, Fei, Xuechao, Ai, Li, Di, Yalan, Luo, Hongjun, Li, Hui, Luo, Wenhong, Lu, Yu, Li, Rui, Duan, Chunli, Gao, Ge, Yang, Hui, Sun, Binggui, He, Rongqiao, Song, Weihong, Han, Hongbin, Tong, Zhiqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838540/
https://www.ncbi.nlm.nih.gov/pubmed/31720368
http://dx.doi.org/10.1016/j.trci.2019.09.007

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