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Discovery of Human Signaling Systems: Pairing Peptides to G Protein-Coupled Receptors
The peptidergic system is the most abundant network of ligand-receptor-mediated signaling in humans. However, the physiological roles remain elusive for numerous peptides and more than 100 G protein-coupled receptors (GPCRs). Here we report the pairing of cognate peptides and receptors. Integrating...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838683/ https://www.ncbi.nlm.nih.gov/pubmed/31675498 http://dx.doi.org/10.1016/j.cell.2019.10.010 |