Single-Molecule Observation of Ligand Binding and Conformational Changes in FeuA

The specific binding of ligands by proteins and the coupling of this process to conformational changes is fundamental to protein function. We designed a fluorescence-based single-molecule assay and data analysis procedure that allows the simultaneous real-time observation of ligand binding and confo...

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Detalles Bibliográficos
Autores principales: de Boer, Marijn, Gouridis, Giorgos, Muthahari, Yusran Abdillah, Cordes, Thorben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838762/
https://www.ncbi.nlm.nih.gov/pubmed/31537314
http://dx.doi.org/10.1016/j.bpj.2019.08.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838762/
https://www.ncbi.nlm.nih.gov/pubmed/31537314
http://dx.doi.org/10.1016/j.bpj.2019.08.005

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