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Single-Molecule Observation of Ligand Binding and Conformational Changes in FeuA
The specific binding of ligands by proteins and the coupling of this process to conformational changes is fundamental to protein function. We designed a fluorescence-based single-molecule assay and data analysis procedure that allows the simultaneous real-time observation of ligand binding and confo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838762/ https://www.ncbi.nlm.nih.gov/pubmed/31537314 http://dx.doi.org/10.1016/j.bpj.2019.08.005 |