DeepHLApan: A Deep Learning Approach for Neoantigen Prediction Considering Both HLA-Peptide Binding and Immunogenicity

Neoantigens play important roles in cancer immunotherapy. Current methods used for neoantigen prediction focus on the binding between human leukocyte antigens (HLAs) and peptides, which is insufficient for high-confidence neoantigen prediction. In this study, we apply deep learning techniques to pre...

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Detalles Bibliográficos
Autores principales: Wu, Jingcheng, Wang, Wenzhe, Zhang, Jiucheng, Zhou, Binbin, Zhao, Wenyi, Su, Zhixi, Gu, Xun, Wu, Jian, Zhou, Zhan, Chen, Shuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838785/
https://www.ncbi.nlm.nih.gov/pubmed/31736974
http://dx.doi.org/10.3389/fimmu.2019.02559

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