Cargando…

Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization

We have previously shown that third-generation antisense (3GA) inhibition of 14q32 microRNA (miRNA)-494 reduced early development of atherosclerosis. However, patients at risk of atherosclerotic complications generally present with advanced and unstable lesions. Here, we administered 3GAs against 14...

Descripción completa

Detalles Bibliográficos
Autores principales: van Ingen, Eva, Foks, Amanda C., Kröner, Mara J., Kuiper, Johan, Quax, Paul H.A., Bot, Ilze, Nossent, Anne Yaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838792/
https://www.ncbi.nlm.nih.gov/pubmed/31689618
http://dx.doi.org/10.1016/j.omtn.2019.09.021

Ejemplares similares