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Antisense Oligonucleotide Inhibition of MicroRNA-494 Halts Atherosclerotic Plaque Progression and Promotes Plaque Stabilization
We have previously shown that third-generation antisense (3GA) inhibition of 14q32 microRNA (miRNA)-494 reduced early development of atherosclerosis. However, patients at risk of atherosclerotic complications generally present with advanced and unstable lesions. Here, we administered 3GAs against 14...
Autores principales: | van Ingen, Eva, Foks, Amanda C., Kröner, Mara J., Kuiper, Johan, Quax, Paul H.A., Bot, Ilze, Nossent, Anne Yaël |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838792/ https://www.ncbi.nlm.nih.gov/pubmed/31689618 http://dx.doi.org/10.1016/j.omtn.2019.09.021 |
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