Developing an Anion Exchange Chromatography Assay for Determining Empty and Full Capsid Contents in AAV6.2

Adeno-associated virus (AAV) vectors are clinically proven gene delivery vehicles that are attracting an increasing amount of attention. Non-genome-containing empty AAV capsids are by-products during AAV production that have been reported to potentially impact AAV product safety and efficacy. Theref...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Chunlei, Mulagapati, Sri Hari Raju, Chen, Zhongying, Du, Jing, Zhao, Xiaohui, Xi, Guoling, Chen, Liyan, Linke, Thomas, Gao, Cuihua, Schmelzer, Albert E., Liu, Dengfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838793/
https://www.ncbi.nlm.nih.gov/pubmed/31720304
http://dx.doi.org/10.1016/j.omtm.2019.09.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838793/
https://www.ncbi.nlm.nih.gov/pubmed/31720304
http://dx.doi.org/10.1016/j.omtm.2019.09.006

Ejemplares similares