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Developing an Anion Exchange Chromatography Assay for Determining Empty and Full Capsid Contents in AAV6.2

Adeno-associated virus (AAV) vectors are clinically proven gene delivery vehicles that are attracting an increasing amount of attention. Non-genome-containing empty AAV capsids are by-products during AAV production that have been reported to potentially impact AAV product safety and efficacy. Theref...

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Detalles Bibliográficos
Autores principales:	Wang, Chunlei, Mulagapati, Sri Hari Raju, Chen, Zhongying, Du, Jing, Zhao, Xiaohui, Xi, Guoling, Chen, Liyan, Linke, Thomas, Gao, Cuihua, Schmelzer, Albert E., Liu, Dengfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838793/ https://www.ncbi.nlm.nih.gov/pubmed/31720304 http://dx.doi.org/10.1016/j.omtm.2019.09.006

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