β-Cyclodextrin complex improves the bioavailability and antitumor potential of cirsiliol, a flavone isolated from Leonotis nepetifolia (Lamiaceae)

Cirsiliol is a flavone found in many Lamiaceae species with high cytotoxic activity against tumor cell lines. Although cirsiliol is being used in cancer therapy, its pharmacological potential is limited by its low solubility and bioavailability. In this paper, a cirsiliol-β-cyclodextrin inclusion co...

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Detalles Bibliográficos
Autores principales: Oliveira, Ana P., Silva, Andressa L.N., Viana, Lucas G.F.C., Silva, Mariana G., Lavor, Érica M., Oliveira-Júnior, Raimundo G., Alencar-Filho, Edilson B., Lima, Ricardo S., Mendes, Rosemairy L., Rolim, Larissa A., Anjos, Débora S.C., Ferraz, Leslie R.M., Rolim-Neto, Pedro J., Silva, Maria F.S., Pessoa, Claudia do Ó., Almeida, Jackson R.G.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838880/
https://www.ncbi.nlm.nih.gov/pubmed/31720439
http://dx.doi.org/10.1016/j.heliyon.2019.e01692

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