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An Engineered AAV6-Based Vaccine Induces High Cytolytic Anti-Tumor Activity by Directly Targeting DCs and Improves Ag Presentation
We have previously shown that an AAV6-based vaccine generates high levels of antigen-specific CD8(+) T cells. Further modifications described here led to significantly increased levels of antigen-specific CD8(+) and CD4(+) T cells, enhanced formation of memory cells, and superior antigen-specific ki...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society of Gene & Cell Therapy
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838889/ https://www.ncbi.nlm.nih.gov/pubmed/31720373 http://dx.doi.org/10.1016/j.omto.2019.10.001 |