AAV-Mediated Expression of AP-1-Neutralizing RNA Decoy Oligonucleotides Attenuates Transplant Vasculopathy in Mouse Aortic Allografts

Transplant vasculopathy (TV), characterized by obstructive lesions in affected vessels, represents one of the long-term complications of cardiac transplantation. Activation of the transcription factor activator protein-1 (AP-1) is implicated in smooth muscle cell (SMC) phenotypic switch from contrac...

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Detalles Bibliográficos
Autores principales: Remes, Anca, Franz, Maximilian, Mohr, Franziska, Weber, Antje, Rapti, Kleopatra, Jungmann, Andreas, Karck, Matthias, Hecker, Markus, Kallenbach, Klaus, Müller, Oliver J., Arif, Rawa, Wagner, Andreas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838891/
https://www.ncbi.nlm.nih.gov/pubmed/31720303
http://dx.doi.org/10.1016/j.omtm.2019.09.009

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