Cargando…
CD8+CD103+ iTregs Inhibit Chronic Graft-versus-Host Disease with Lupus Nephritis by the Increased Expression of CD39
Many patients with systemic lupus erythematosus (SLE) have lupus nephritis, one of the severe complications of SLE. We previously reported that CD8+CD103+ T regulatory cells induced ex vivo with transforming growth factor β (TGF-β) (iTregs) inhibited immune cells responses to ameliorate excessive au...
Autores principales: | Zhang, Xiao, Ouyang, Xia, Xu, Zhenjian, Chen, Junzhe, Huang, Qiuyan, Liu, Ya, Xu, Tongtong, Wang, Julie, Olsen, Nancy, Xu, Anping, Zheng, Song Guo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838901/ https://www.ncbi.nlm.nih.gov/pubmed/31402273 http://dx.doi.org/10.1016/j.ymthe.2019.07.014 |
Ejemplares similares
-
Rapamycin Regulates iTreg Function through CD39 and Runx1 Pathways
por: Lu, Yunjie, et al.
Publicado: (2014) -
TGF-β-Induced CD8(+)CD103(+) Regulatory T Cells Show Potent Therapeutic Effect on Chronic Graft-versus-Host Disease Lupus by Suppressing B Cells
por: Zhong, Haowen, et al.
Publicado: (2018) -
P38 MAP Kinase Signaling Is Required for the Conversion of CD4+CD25− T Cells into iTreg
por: Huber, Samuel, et al.
Publicado: (2008) -
Efficient induction of CD25(- )iTreg by co-immunization requires strongly antigenic epitopes for T cells
por: Geng, Shuang, et al.
Publicado: (2011) -
In-vitro inhibition of IFNγ(+) iTreg mediated by monoclonal antibodies against cell surface determinants essential for iTreg function
por: Daniel, Volker, et al.
Publicado: (2012)