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Preparation and effect of lyophilized platelet-rich fibrin on the osteogenic potential of bone marrow mesenchymal stem cells in vitro and in vivo

OBJECTIVES: The goal of this study was to prepare lyophilized platelet-rich fibrin (L-PRF) and analyze the combined use of L-PRF and osteogenic bone marrow mesenchymal stem cell (BMSC) sheet fragments for bone tissue engineering via in vivo injection. METHODS: First, fresh PRF (F-PRF) was lyophilize...

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Detalles Bibliográficos
Autores principales: Wang, Zhifa, Han, Leng, Sun, Tianyu, Wang, Weijian, Li, Xiao, Wu, Buling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838904/
https://www.ncbi.nlm.nih.gov/pubmed/31720476
http://dx.doi.org/10.1016/j.heliyon.2019.e02739