A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture

Epidemiological evidence shows that physical activity lowers the risk of developing breast cancer and decreases the risk of disease recurrence [1,2]. The main hypothesis on the positive effects of exercise-oncology has focused on lowering the basal systemic levels of cancer risk factors with exercis...

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Autores principales: De Santi, Mauro, Baldelli, Giulia, Lucertini, Francesco, Natalucci, Valentina, Brandi, Giorgio, Barbieri, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Medicine and Dentistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838928/
https://www.ncbi.nlm.nih.gov/pubmed/31720346
http://dx.doi.org/10.1016/j.dib.2019.104704
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author De Santi, Mauro
Baldelli, Giulia
Lucertini, Francesco
Natalucci, Valentina
Brandi, Giorgio
Barbieri, Elena
author_facet De Santi, Mauro
Baldelli, Giulia
Lucertini, Francesco
Natalucci, Valentina
Brandi, Giorgio
Barbieri, Elena
author_sort De Santi, Mauro
collection PubMed
description Epidemiological evidence shows that physical activity lowers the risk of developing breast cancer and decreases the risk of disease recurrence [1,2]. The main hypothesis on the positive effects of exercise-oncology has focused on lowering the basal systemic levels of cancer risk factors with exercise training. Recently, the effects of cancer progression control by components released after acute exercise bouts have gained attention [3,4]. However, the evaluation of the antiproliferative potential of a single exercise bout needs technical improvement. Here, we present data of a pilot study showing how to evaluate the anti-cancer potential of single exercise bouts with an in vitro three-dimensional cell growth assay, using a triple-negative breast cancer cell line cultured with exercise-conditioned serum.
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spelling pubmed-68389282019-11-12 A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture De Santi, Mauro Baldelli, Giulia Lucertini, Francesco Natalucci, Valentina Brandi, Giorgio Barbieri, Elena Data Brief Medicine and Dentistry Epidemiological evidence shows that physical activity lowers the risk of developing breast cancer and decreases the risk of disease recurrence [1,2]. The main hypothesis on the positive effects of exercise-oncology has focused on lowering the basal systemic levels of cancer risk factors with exercise training. Recently, the effects of cancer progression control by components released after acute exercise bouts have gained attention [3,4]. However, the evaluation of the antiproliferative potential of a single exercise bout needs technical improvement. Here, we present data of a pilot study showing how to evaluate the anti-cancer potential of single exercise bouts with an in vitro three-dimensional cell growth assay, using a triple-negative breast cancer cell line cultured with exercise-conditioned serum. Elsevier 2019-10-21 /pmc/articles/PMC6838928/ /pubmed/31720346 http://dx.doi.org/10.1016/j.dib.2019.104704 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Medicine and Dentistry
De Santi, Mauro
Baldelli, Giulia
Lucertini, Francesco
Natalucci, Valentina
Brandi, Giorgio
Barbieri, Elena
A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
title A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
title_full A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
title_fullStr A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
title_full_unstemmed A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
title_short A dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
title_sort dataset on the effect of exercise-conditioned human sera in three-dimensional breast cancer cell culture
topic Medicine and Dentistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838928/
https://www.ncbi.nlm.nih.gov/pubmed/31720346
http://dx.doi.org/10.1016/j.dib.2019.104704
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