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Effective In Vivo Gene Modification in Mouse Tissue-Resident Peritoneal Macrophages by Intraperitoneal Delivery of Lentiviral Vectors

Tissue-resident macrophages exhibit specialized phenotypes dependent on their in vivo physiological niche. Investigation of their function often relies upon complex whole mouse transgenic studies. While some appropriate lineage-associated promoters exist, there are no options for tissue-specific tar...

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Detalles Bibliográficos
Autores principales: Ipseiz, Natacha, Czubala, Magdalena A., Bart, Valentina M.T., Davies, Luke C., Jenkins, Robert H., Brennan, Paul, Taylor, Philip R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838965/
https://www.ncbi.nlm.nih.gov/pubmed/31720306
http://dx.doi.org/10.1016/j.omtm.2019.10.004

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