ICOS Costimulation at the Tumor Site in Combination with CTLA-4 Blockade Therapy Elicits Strong Tumor Immunity

Cytotoxic T lymphocyte-associated protein 4 (CTLA-4) blockade therapy is able to induce long-lasting antitumor responses in a fraction of cancer patients. Nonetheless, there is still room for improvement in the quest for new therapeutic combinations. ICOS costimulation has been underscored as a poss...

Descripción completa

Detalles Bibliográficos
Autores principales: Soldevilla, Mario Martínez, Villanueva, Helena, Meraviglia-Crivelli, Daniel, Menon, Ashwathi Puravankara, Ruiz, Marta, Cebollero, Javier, Villalba, María, Moreno, Beatriz, Lozano, Teresa, Llopiz, Diana, Pejenaute, Álvaro, Sarobe, Pablo, Pastor, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838990/
https://www.ncbi.nlm.nih.gov/pubmed/31405808
http://dx.doi.org/10.1016/j.ymthe.2019.07.013

Ejemplares similares

Ejemplares similares