A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives

The flourishing advancements in nanotechnology significantly boost their application in biomedical fields. Whereas, inorganic nanomaterials are normally prepared and capped with hydrophobic ligands, which require essential surface modification to increase their biocompatibility and endow extra funct...

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Detalles Bibliográficos
Autores principales: Gu, Shiwei, Guo, Chang, Wang, Hui, Tian, Guangjun, Xu, Suying, Wang, Leyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839036/
https://www.ncbi.nlm.nih.gov/pubmed/31737607
http://dx.doi.org/10.3389/fchem.2019.00734
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author Gu, Shiwei
Guo, Chang
Wang, Hui
Tian, Guangjun
Xu, Suying
Wang, Leyu
author_facet Gu, Shiwei
Guo, Chang
Wang, Hui
Tian, Guangjun
Xu, Suying
Wang, Leyu
author_sort Gu, Shiwei
collection PubMed
description The flourishing advancements in nanotechnology significantly boost their application in biomedical fields. Whereas, inorganic nanomaterials are normally prepared and capped with hydrophobic ligands, which require essential surface modification to increase their biocompatibility and endow extra functions. Phenylboronic acid derivatives have long been known for its capacity for selective recognition of saccharides. Herein, we demonstrated a versatile surface modification strategy to directly convert hydrophobic inorganic nanocrystals into water-dispersible and targeting nanocomposites by employing boronic acid modified photo-polymerizable 10,12-pentacosadiynoicacid and further explore its potentials in selective cancer cell imaging.
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spelling pubmed-68390362019-11-15 A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives Gu, Shiwei Guo, Chang Wang, Hui Tian, Guangjun Xu, Suying Wang, Leyu Front Chem Chemistry The flourishing advancements in nanotechnology significantly boost their application in biomedical fields. Whereas, inorganic nanomaterials are normally prepared and capped with hydrophobic ligands, which require essential surface modification to increase their biocompatibility and endow extra functions. Phenylboronic acid derivatives have long been known for its capacity for selective recognition of saccharides. Herein, we demonstrated a versatile surface modification strategy to directly convert hydrophobic inorganic nanocrystals into water-dispersible and targeting nanocomposites by employing boronic acid modified photo-polymerizable 10,12-pentacosadiynoicacid and further explore its potentials in selective cancer cell imaging. Frontiers Media S.A. 2019-11-01 /pmc/articles/PMC6839036/ /pubmed/31737607 http://dx.doi.org/10.3389/fchem.2019.00734 Text en Copyright © 2019 Gu, Guo, Wang, Tian, Xu and Wang. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Gu, Shiwei
Guo, Chang
Wang, Hui
Tian, Guangjun
Xu, Suying
Wang, Leyu
A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives
title A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives
title_full A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives
title_fullStr A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives
title_full_unstemmed A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives
title_short A Versatile Strategy for Surface Functionalization of Hydrophobic Nanoparticle by Boronic Acid Modified Polymerizable Diacetylene Derivatives
title_sort versatile strategy for surface functionalization of hydrophobic nanoparticle by boronic acid modified polymerizable diacetylene derivatives
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839036/
https://www.ncbi.nlm.nih.gov/pubmed/31737607
http://dx.doi.org/10.3389/fchem.2019.00734
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