Bee Venom Soluble Phospholipase A2 Exerts Neuroprotective Effects in a Lipopolysaccharide-Induced Mouse Model of Alzheimer’s Disease via Inhibition of Nuclear Factor-Kappa B

Neuroinflammation is important in the pathogenesis and development of Alzheimer’s disease (AD). In the AD brain, microglial activation and upregulation of pro-inflammatory mediators both induce amyloid beta (Aβ) accumulation. Regulatory T cells (Tregs) and nuclear factor-kappa B (NF-κB) signaling ha...

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Detalles Bibliográficos
Autores principales: Ham, Hyeon Joo, Han, Ji Hye, Lee, Yong Sun, Kim, Ki Cheon, Yun, Jaesuk, Kang, Shin Kook, Park, YangSu, Kim, Se Hyun, Hong, Jin Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6839038/
https://www.ncbi.nlm.nih.gov/pubmed/31736738
http://dx.doi.org/10.3389/fnagi.2019.00287

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